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Saturday, July 20, 2013

Erythrocyte Sedimentation Rate

Erythrocyte sedimentation rate (ESR) AKA  sedimentation rate or Westergren ESR, is the rate at which red blood cells sediment/precipitate in a duartion of one hour. It is a very common blood test, and is a NON-specific measure of inflammation. In order to conduct this test, anticoagulated blood is placed in an upright tube, known as a Westergren tube, and the rate at which the red blood cells fall is measured and reported in mm/h. 

Diagnostic Use: 

 ESR increased can be triggered  by any cause or focus of inflammation.It may be increased in pregnancy, inflammation, anemia or rheumatoid arthritis. However it may  be  decreased in polycythemia, sickle cell anemia, hereditary spherocytosis, and congestive heart failure. Studies reiterated that it may be increased in kidney cancer.It should be taken note that basal ESR is slightly higher in females(Medline).

Commonly Use:

 useful in diagnosing some diseases such as:
 multiple myeloma, 
temporal arteritis,
 polymyalgia rheumatica,
 systemic lupus erythematosus, 
rheumatoid arthritis,
chronic kidney diseases.

 In many of such cases, the ESR may exceed 100 mm/hour.


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